Medico chirurgo laureato nel 2017 presso lʼUniversità di Chieti Gabriele DʼAnnunzio, con tesi in Procreazione Medicalmente Assistita sullʼutilizzo dei...

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Formazione

Università degli studi di Torino

Specializzazioni

Ginecologia e Ostetricia

Tirocini

NYU University - Langone Medical Center - Manhattan

Certificati

Foto

Competenze linguistiche

Italiano,
Inglese

Premi e riconoscimenti

Profili social

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Pubblicazioni e articoli

Pubblicazioni (6)

Elsevier · 3 ott 2022 - Management of Infertility: A Practical Approach: this book offers an accurate and complete reference for the management of infertility and a robust step-by-step guide for assisted reproduction technologies (ARTs), including how to plan, design and organize a clinical setting and laboratory. The book also provides an evidence-based, complete and practical description of the available methods for diagnosis and management of male and female infertility. This will be an ideal resource for researchers, students and clinicians who want to gain complete knowledge about both basic and advanced information surrounding the diagnosis and management of infertility and related disorders. Provides a step-by-step guide on how to design, plan and organize an Assisted Reproductive Technology (ART) unit and laboratory, deeply discusses both male and female factor infertility, providing a complete guide for the diagnosis and treatment of the different causes of infertility, addresses all the techniques of assisted reproduction and in vitro fertilization, discussing their use in different clinical settings.

JCM - Journal of Clinical Medicine · 12 mar 2022 - Effect of rLH Supplementation during Controlled Ovarian Stimulation for IVF: Evidence from a Retrospective Analysis of 1470 Poor/Suboptimal/Normal Responders Receiving Either rFSH plus rLH or rFSH Alone: We retrospectively studied a real-life population of 1470 women undergoing IVF, with poor/suboptimal/normal ovarian responsiveness to controlled ovarian stimulation (COS), comparing the cumulative live birth rate (cLBR) when COS was performed using rFSH alone or rFSH + rLH in a 2:1 ratio. Overall, we observed significantly higher cLBR in the rFSH alone group than in the rFSH + rLH group (29.3% vs. 22.2%, p

JCM - Journal of Clinical Medicine · 6 feb 2022 - Women in advanced reproductive age: are the follicular output rate, the follicle‐oocyte index and the ovarian sensitivity index predictors of live birth in an IVF cycle?: Several researchers have investigated alternative markers related to ovarian responsiveness in order to better predict IVF outcomes, particularly in advanced reproductive- aged women. The follicular output rate (FORT), the follicle-oocyte index (FOI) and the ovarian sensitivity index (OSI) are among the most promising. However, these three metrics have not been investigated as independent predictors of live birth in women of advanced reproductive age; neither have they been compared to the two ‘component’ characteristics that are used to calculate them. (2) Methods: A logistic regression model containing all relevant predictors of ovarian reserve or response was used to evaluate the potential of FORT, FOI and OSI as predictors of live birth. After, the non-linear associations between FORT, FOI and OSI and the probability of live birth were evaluated. Finally, we fitted multiple logistic regression models to compare whether FORT, FOI and OSI were more informative predictors than their components. (3) Results: 590 couples received a total of 740 IVF cycles, after which, 127 (17.5%) obtained a live birth. None of FORT, FOI and OSI showed a strength of association or a p-value even close to female age (odds ratio for live birth (95% confidence interval) 1.00 (0.99–1.01), 1.00 (0.99–1.01), 0.98 (0.88–1.11) and 0.58 (0.48–0.72), respectively). The three models comparing FORT, FOI and OSI with the number of oocytes retrieved, the AFC, the number of preovulatory follicles and the FSH total dose were not more informative. (4) Conclusions: In a population of women of advanced age with unexplained infertility, none of FORT, FOI and OSI were predictive of live birth or more predictive than the two ‘component’ characteristics that were used to calculate them. We suggest clinicians and researchers still use female age as the most reliable predictor of an IVF treatment.

Uterine Fibroids: from diagnosis to treatment - Nova Medicine Health · 17 feb 2021 - Impact, Management and treatment of Uterine Myomas in Infertile Couples: Uterine fibroids (UFs) are benign masses that develop from the smooth muscle cells and connective tissue of the wall of the uterus under the influence of genetic and / or hormonal stimuli. These benign tumors are postulated to arise from a single, genetically altered, mesenchymal cell under the influence of gonadal hormones namely progesterone and estradiol. The annual societal cost for fibroids is estimated up to 34 billion dollars, calculated through combined expenditures for medical management of symptomatic fibroids, lost work attributable to diagnosis of fibroids, and obstetrical complications of fibroids In Italy, for example, they afflict 3 million women. Estimates say that 20 to 80% of women experience them throughout life, and are the most common form of benign cancer in childbearing age. Various surgical and medical options are currently available to manage symptomatic uterine fibroids. The choice of the appropriate therapeutic approach for UFs depends on several factors, including women’s age, parity, childbearing aspirations and wish to preserve fertility, extent and severity of symptoms, size, number and location of myomas, risk of malignancy and proximity to menopause. This book reviews the diagnoses, management and treatment of uterine fibroids.

Reproductive Sciences · 22 dic 2020 - Expectant management before in vitro fertilization in women aged 39 or above and unexplained infertility does not decrease live birth rates compared to immediate treatment”“Expectant management before in vitro fertilization in women aged 39 or above and unexplained infertility does not decrease live birth rates compared to immediate treatment: Unexplained infertile couples can have further expectant management before starting assisted reproductive treatments. However, ovarian reserve and in vitro fertilization (IVF) outcomes rapidly decline after 39 years or more. It is thus important to clarify whether a waiting policy is also appropriate for women of advanced age. Couples who had access to a waiting list for approximately 1 year before receiving reimbursed public IVF were compared with those paying for access to immediate treatment. To allow for comparisons between these two strategies, we followed up couples who opted to pay for 1 year after the last embryo transfer from their first cycle. We calculated the proportion of live births in both groups and compared these using logistic regression models and a two-sample Z test for equality of proportions. Six hundred thirty-five couples were evaluated. Out of 359 couples in the immediate group, 70 (19.5%) had a live birth of which 11 after natural conception and 59 after IVF. Out of 276 couples in the waiting group, 57 (20.7%) had a live birth of which 37 after natural conception and 20 after IVF. There was no statistically significant difference between the two strategies in terms of the crude cumulative live birth rate (cLBR). The adjusted odds ratio of 0.69 (95%CI:0.39–1.22) did not change this conclusion as our sensitivity analyses. The cLBR for the ‘waiting before IVF’ and the ‘immediate’ strategies were similar. Further studies are needed to better characterize couples affected by unexplained infertility in order to individualize treatment strategies.

JCM - Journal of Clinical Medicine · 24 lug 2020 - Effect of a Combination of Myo‐Inositol, Alpha‐Lipoic Acid, and Folic Acid on Oocyte Morphology and Embryo Morphokinetics in non‐PCOS Overweight/Obese Patients Undergoing IVF: A Pilot, Prospective, Randomized Study: Herein we aimed at assessing whether Myo-Inositol (MI), Alpha–Lipoic acid (ALA), and Folic acid (FA) could improve oocyte quality and embryo development in non-PCOS overweight/obese women undergoing IVF. Three hundred and twenty-four mature oocytes were obtained from non-PCOS overweight/obese patients, randomized to receive either MI, ALA, and FA (MI + ALA + FA group, n = 155 oocytes) or FA alone (FA-only group, n = 169 oocytes). Oocytes were examined using Polarized Light Microscopy to assess morphological features of zona pellucida (ZP) and meiotic spindle (MS). One hundred and seventy-six embryos (n = 84 in the MI + ALA + FA group, n = 92 in the FA-only group) were assessed by conventional morphology on days 2 and 5, as well as using the Time-Lapse System morphokinetic analysis. A significantly higher ZP retardance, area, and thickness (p

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Falcone Rossella Daisy

Profilo verificato

24 aprile 2024 • Visita prenotata su MioDottore.it

• Presso: Altro • Altro

Ho portato mia figlia tredicenne per la sua prima visita e la dottoressa Non solo è riuscita a farla sentire a proprio agio ma è stata di Una bravura e una delicatezza che non ho mai trovato fino ad oggi credo resterà la nostra dottoressa per il resto del tempo

Marinella P

Profilo verificato

28 marzo 2024 • Visita prenotata su MioDottore.it

• Presso: CASA DELLA SALUTE • Prima Visita

La mia prima visita con lei. Molto professionale nonostante la giovane età. Soddisfatta dell attenzione verso il mio problema dove è riuscita a portarmi serenità. Ci ritornerò sicuramente. Grazie.

Beatrice

26 marzo 2024

Presso: Altro • Altro

La Dott.ssa Mercaldo è sempre stata una persona disponibile, professionale, empatica ma anche molto dolce con mia moglie nello spiegare in maniera dettagliata e semplice tutte le informazioni di cui avevamo bisogno. Consiglio vivamente una consulenza e una visita da lei in caso di necessità e non chiarezza delle informazioni. Finalmente ho visto mia moglie soddisfatta delle risposte e spiegazioni chiare.

C.C

Profilo verificato

14 febbraio 2024 • Visita prenotata su MioDottore.it

• Presso: CASA DELLA SALUTE • check-up ginecologico

Empatia, comprensione, rispetto, cortesia e competenza. Visita perfetta.

Beatrice

2 novembre 2023

Presso: CASA DELLA SALUTE • visita ginecologica di controllo

Mette a proprio agio durante la visita, avvenuta puntuale rispetto all’ orario previsto. Traspare competenza e professionalità

Paola Pittau

26 ottobre 2023

Presso: Altro • Altro

Gentile chiara nell esposizione puntuale , ispira fiducia e rincuora

A.P.

18 ottobre 2023

Presso: CASA DELLA SALUTE • visita ginecologica per sterilità

La Dottoressa si è dimostrata molto scrupolosa ed empatica come pochi altri.

Claretta

16 ottobre 2023

Presso: CASA DELLA SALUTE • Altro

Grande gentilezza, cortesia ed empatia. La sicurezza, tranquillità e pacatezza della dottoressa mi hanno fatto sentire subito a mio agio e la sua disponibilità a darmi tutte le informazioni e rispondere alle mie domande mi hanno dato serenità e piena fiducia.

Carmela martella

16 ottobre 2023

Presso: CASA DELLA SALUTE • check-up ginecologico

Personale cordiale e disponibile,inoltre professionista scrupolosa e molto preparata

Anna P

Profilo verificato

16 ottobre 2023

Presso: Altro • Altro

La dottoressa è molto preparata, attenta e gentile. Spiegazioni precise e puntuali. Bei modi che aiutano a mettere a proprio agio. Scrupolosa negli esami prescritti e nella valutazione degli stessi.
Mi sono sin da subito sentita a mio agio, trattata con cura e in buone mani.
La consiglio sicuramente

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Medico chirurgo laureato nel 2017 presso lʼUniversità di Chieti Gabriele DʼAnnunzio, con tesi in Procreazione Medicalmente Assistita sullʼutilizzo dei GnRH antagonisti nei protocolli flessibili di stimolazione ovarica con votazione di 110/110 cum
laude e menzione accademica.

Da novembre 2023 specialista in Ginecologia e Ostetricia, attualmente ginecologa specializzata in Medicina della Riproduzione e Procreazione Medicalmente Assistita presso la clinica LIVET – Genera di Torino.

In dieci anni di esperienza nel settore della Medicina della Riproduzione ho sviluppato interesse e dedizione nella ricerca clinica, pubblicando diversi lavori scientifici su riviste peer review di notevole impatto internazionale, fino ad essere citata nelle nuove linee guida 2022 ESHRE (European Society of Human Reproduction and Embryology) per la gestione dell’infertilità inspiegata, nella sezione “IVF vs expectant management” (pag.76 - https://www.eshre.eu/-/media/sitecore-files/Guidelines/UI/Unexplained-infertility-
guideline_draft-for-review.pdf?la=en&hash=D88D81DE5DABB0236D076C05492B2266C99F30DA).

Lavori di ricerca pubblicati tra il 2019 e il 2022:
- “Effect of a Combination of Myo-Inositol, Alpha-Lipoic Acid, and Folic Acid on Oocyte Morphology and Embryo Morphokinetics in non-PCOS Overweight/Obese Patients Undergoing IVF: A Pilot, Prospective, Randomized Study”, Journal of Clinical Medicine (DOI: 10.3390/jcm9092949)
- “Expectant management before in vitro fertilization in women aged 39 or above and unexplained infertility does not decrease live birth rates compared to immediate treatment”, Reproductive Sciences (DOI: 10.1007/s43032-021-00767-0)
- “Uterine Fibroids, from diagnosis to treatment” edizione Nova Medicine Health, nella sezione: “Impact, Management and treatment of Uterine Myomas in Infertile Couples” (https://novapublishers.com/shop/uterine-fibroids-from-diagnosis-to-treatment/)
- “Women in advanced reproductive age: are the follicular output rate, the follicle-oocyte index and the ovarian sensitivity index predictors of live birth in an IVF cycle?” Journal of Clinical Medicine (DOI: 10.3390/jcm11030859)
- “Effect of rLH Supplementation during Controlled Ovarian Stimulation for IVF: Evidence from a Retrospective Analysis of 1470
Poor/Suboptimal/Normal Responders Receiving Either rFSH plus rLH or rFSH Alone” Journal of Clinical Medicine (DOI: 10.3390/jcm11061575>)
- “Management of Infertility” edizione Elsevier - capitolo: preparation of the couple for the ART technique: necessary and unnecessary tests (https://www.elsevier.com/books/management-of-infertility/lagana/978-0-323-8990 7-9)

Nell’edizione ESHRE 2020 - European Society of Human Reproduction and Embriology ho presentato l’abstract intitolato:
- “Ovarian Stimulation with rFSH+rLH vs. rFSH alone in poor/suboptimal/normal responders undergoing IVF: real life analysis of
1382 patients stratified for the number of retrieved oocytes”

Ad ottobre 2021 relatrice al congresso nazionale SIFES e MR - Società Italiana di Fertilità e Sterilità e Medicina della Riproduzione, con l’abstract dello studio svolto in collaborazione con l’Università di Amsterdam UMC - Centre for Reproductive Medicine:
- “FORT (Follicular Output Rate), FOI (Follicle-Oocyte Index) E OSI (Ovarian Sensitivity Index) come fattori predittivi di Live Birth Rate in età materna avanzata"

Attualmente svolgo la mia attività professionale presso la clinica LIVET – Genera di Torino con specializzazione in Medicina della Riproduzione e Procreazione Medicalmente Assistita.

Fin dai primi anni della mia carriera universitaria ho sempre sentito di volermi dedicare alla cura della salute della donna. Ho il privilegio di avere un ruolo in cui mi viene concesso di sfiorare la vita e i sogni delle persone. Ogni bambino che nasce è un’eco di questo privilegio e ogni fallimento è un incoraggiamento a fare sempre meglio.